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Home Credits/Funding Data Collections Quality Assurance Protocol Usage Agreement List of Requests for Restricted Data Collections Request Access & More Information

A growing body of research has documented the utility of magnetic resonance imaging technologies to support in vivo examination of brain organization and function in the nonhuman primate. Recent efforts have not only demonstrated the ability to recapitulate the findings of postmortem examinations, but also to provide novel insights into the organizational principles of nonhuman primate connectome and the functional interactions within it. These gains could only be made through in vivo studies. These advances are timely given the growing prominence of translational and comparative neuroscience studies in large-scale national and international initiatives focused on advancing our understanding of human brain function and ability to generate novel therapeutics for neurology and psychiatry.

Despite demonstrable feasibility and utility, the field of nonhuman primate imaging is only its infancy. Numerous challenges related to the acquisition and processing are still in the process of being worked out, and the bounds of what can be accomplished are only beginning to be explored. In this regard, the overarching goal of PRIMatE Data Exchange (PRIME-DE) is to create an open science resource for the neuroimaging community that will facilitate the mapping of the non-human primate connectome. To accomplish this, we will aggregate a combination of functional, diffusion and morphometric magnetic resonance imaging (MRI) datasets across laboratories around the world, and share the data with the larger scientific community.

The various webpages on the present site are intended to be informative regarding the PRIMatE Data Exchange (PRIME-DE). However, prior to data usage, we strongly recommend that you download and read the PRIMatE Data Exchange Data Descriptor.

Credits

  • Directors
    Daniel Margulies1, Michael Milham2,3, Charlie Schroeder3,4
  • Project Management
    Michael Milham2,3
  • Data organization
    Lei Ai2, Bonhwang Koo2, Ting Xu2,3
  • Logo
    Stacey Ascher2
  1. Centre National de la Recherche Scientifique (CNRS) UMR 7225, Institut du Cerveau et de la Moelle épinière, Paris, France
  2. Center for the Developing Brain, Child Mind Institute, New York, New York, United States of America
  3. Center for Biomedical Imaging and Neuromodulation at the Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York, United States of America
  4. Departments of Neurosurgery and Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, the United States of America

Funding

Primary support for the work by Michael P. Milham and the INDI team was provided by gifts from Joseph P. Healy to the Child Mind Institute, as well as by the BRAIN Initiative (R01MH111439). MPM is a Randolph Cowen and Phyllis Green Scholar.

Primary support for the work by Charles Schroeder is provided by the BRAIN Initiative (R01MH111439) and the Sylvio O. Conte Center “Neurobiology and Dynamics of Active Sensing” (P50MH109429).

Primary support for the work by Daniel Margulies is provided by the Max Planck Society.

Data Collections

Aix-Marseille Université California Institute of Technology East China Normal University - Chen East China Normal University - Kwok Institute of Neuroscience Institut des Sciences Cognitives Marc Jeannerod Lyon Neuroscience Research Center McGill University Mount Sinai School of Medicine Mount Sinai School of Medicine Nathan Kline Institute National Institute of Mental Health National Institute of Mental Health Netherlands Institute for Neuroscience NeuroSpin Newcastle University Oregon Health and Science University Princeton University Rockefeller University Stem Cell and Brain Research Institute University of California, Davis University of Minnesota University of Oxford NIN Primate Brain Bank/Utrecht University University of Western Ontario
Investigators Brochier
Sein
Rajimehr
Tsao
Chen Kwok
Zhou
Wang Ben Hamed
Hiba
Hadj-Bouziane
Meunier
Guedj
Mok
Rudko
Shmuel
Croxson
Fleysher
Croxson
Fleysher
Froudist-Walsh
Damatac
Nagy
Schroeder
Milham
Leopold
Russ
Messinger
Jung
Seidlitz
Ungerleider
Klink
Roelfsema
Jarraya
Dehaene
Petkov
Nacef
Thiele
Poirier
Balezeau
Griffiths
Schmid
Rios
Sullivan
Fair
Kastner
Pinsk
Schwiedrzik
Freiwald
Zarco
Procyk
Wilson
Amiez
Baxter
Croxson
Morrison
Yacoub
Harel
Sallet
Mars
Rushworth
Navarrete
Blezer
Todorov
Lindenfors
Laland
Reader
Everling
Menon
Species Macaca mulatta Macaca mulatta Macaca mulatta Macaca mulatta Macaca mulatta, Macaca fascicularis Macaca mulatta Macaca mulatta Macaca mulatta, Macaca fascicularis Macaca mulatta, Macaca fascicularis Macaca mulatta Macaca mulatta Macaca mulatta Macaca mulatta Macaca mulatta Macaca mulatta Macaca mulatta Macaca mulatta Macaca mulatta Macaca mulatta, Macaca fascicularis Macaca mulatta, Macaca fascicularis Macaca mulatta Macaca mulatta Macaca mulatta See site page Macaca mulatta
Subjects 4 2 10 4 8 8 4 3 8 5 2 3 3 2 3 14 2 2 6 22 19 2 20 51 12
Scanner Siemens Prisma 3T Siemens TIM Trio 3T Siemens TIM Trio 3T Siemens TIM Trio 3T Siemens TIM Trio 3T Siemens Sonata 1.5T

Siemens Prisma 3T
Siemens Sonata 1.5T

Siemens Prisma 3T
Siemens TIM Trio 3T Philips Achieva 3T Siemens Skyra 3T Siemens TIM Trio 3T Bruker BioSpec Vertical 4.7T Bruker Biospec Vertical 4.7T Philips Ingenia 3T Siemens TIM Trio

Siemens Prisma Fit
Bruker Vertical 4.7T Siemens Tim Trio 3T Siemens Prisma VE11C 3T Siemens Tim Trio 3T Siemens Sonata 1.5T

Siemens Prisma 3T
Siemens Skyra 3T Siemens Syngo B17 7T [Undisclosed] 3T Varian small-bore 9.4T

Siemens Magnetom Trio 3T
Siemens Magnetom 7T
State Anesthetized Awake Anesthetized Anesthetized Anesthetized Anesthetized/Awake Awake Anesthetized Anesthetized Anesthetized Anesthetized/Awake Awake Anesthetized/Awake Anesthetized Anesthetized Anesthetized/Awake Anesthetized Anesthetized Anesthetized Anesthetized Anesthetized Anesthetized Anesthetized Post-mortem Anesthetized
Structural T1
Structural T2
Resting State fMRI 8 min 20-40 min 43 min 76-155 min 30-150 min 10-15 min 9.7 min 21.6 min 480 min 60 min 80 min 13.5 min 27 min 53.43 min 60 min
Naturalistic Viewing fMRI 96 min 55-345 min 170 min
Task fMRI
Fieldmap
Diffusion MRI
Magnetic Resonance Spectroscopy
Processed Data Cortical Thickness
Template Provided
Usage Agreement CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA DUA DUA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA CC-BY-NC-SA
(See page for additional details)
CC-BY-NC-SA CC-BY-NC-SA
Collection Details

Quality Assurance Protocol

Consistent with recent major FCP/INDI data releases, we made use of the Preprocessed Connectome Project Quality Assurance Protocol (QAP; Shehzad et al., 2013) to assess data quality for core MRI data modalities (i.e., functional MRI, morphometry MRI and diffusion MRI). More information about the quality control process used for HBN MRI data can be found at the PCP Quality Assurance Protocol webpage.

Usage Agreement

Data usage policies differ among the data collections to PRIME depending on the specific institutional and collaborative requirements identified by their contributions. For each collection, the contributor has set the sharing permissions for their data using one or more the following four policies. Usage policies are specified in the Data Collections Summary Table as well as on the individual webpages for the varying collections.

  1. Creative Commons – Attribution-NonCommercial Share Alike (CC-BY-NC-SA)
    Standard INDI data sharing policy. Prohibits use of the data for commercial purposes.
  2. Creative Commons – Attribution (CC-BY)
    Least restrictive data sharing policy.
  3. Custom Data Usage Agreement (DUA)
    Users must complete a data usage agreement (DUA) prior to gaining access to the data. Contributors can customize the agreement as they see fit, including determining whether or not signatures from authorized institutional official are required prior to executing the DUA.

Request Access & More Information

Given the increased amount of information provided in the INDI datasets, we are requiring that individuals register with the 1000 Functional Connectomes Project website on NITRC to gain access to the INDI datasets. Upon successful registration, users will have full access to the datasets, and the right to unrestricted usage of the datasets for non-commercial purposes, just as before. Click here to request access to the 1000 Functional Connectomes Project on NITRC. Users will be approved within 1 business day.